Gas is injected down the side string, which runs parallel to the production tubing and communicated with the gas lift mandrel in installation. The injected gas travels down the side string, regulated through a gas lift valve and into the fluid column inside the tubing. The purpose of this application is to isolate the annulus from gas injection pressure. This application is best for wells with damaged casing and wells where gas has to be vented up the annular area.

Treatment chemicals are pumped downhole into the produced fluids of a well to control harmful deposits. A chemical injection line may be run from the chemical injection mandrel to the surface to act as a conduit for the treatment fluids. A high-pressure pump installed at the surface is used to pump the treatment fluid downhole. This application is best for preventing corrosive degradation.

Water is pumped into the tubing. The water travels down the tubing and is regulated into each zone being flooded. With waterflood regulators, multiple zones can be flooded with a single wellbore. Waterflood is used to maintain or increase reservoire pressure in zones that oil production has or is expected to decline.